20+ years of applied mycology. A division of Crowe Logic, Inc.

The PhD-Quantized
Knowledge Lake
for psychedelic drug discovery.

Fifteen Schedule I compounds, PubMed-cited. Twenty-nine PhD-trained AI expert agents, grounded in real literature and federal regulation. A DEA Schedule I application drafted in two weeks, not three months.

Built by Michael Crowe, founder of Southwest Mushrooms, author of The Mushroom Grower, principal architect of CriOS Nova and the Crowe Logic AI platform.

0compounds in the
knowledge lake
0PhD-trained
AI expert agents
0+PubMed citations
inline-grounded
0artifacts per
DEA reg-pack
0cultivar and
strain profiles
0weeks from intake
to delivery

The platform

A working commercial stack built on top of CriOS Nova, Crowe Logic's chemoinformatics engine, and a 194-agent architecture specialized for psychedelic tryptamines, phenethylamines, ergolines, and related scaffolds.

Compound knowledge base

Fifteen Schedule I and adjacent compounds. Each carries PubMed-cited receptor binding data, metabolic pathways, drug interactions, toxicology, and FDA status. Queryable by target, potency, or class.

29 expert agents

Twenty-four Molecular Design specialists, three Psychedelic Specialists, and two Core orchestrators. Each one is an AI composite persona grounded in real literature. The reasoning is PhD-grade; the disclosure is honest.

Cultivation intelligence

Six Psilocybe species and six commercial P. cubensis strains with peer-reviewed alkaloid profiles. Match a target alkaloid profile to ranked cultivar and strain candidates with predicted dry-weight percentages.

Try the platform, live in your browser.

Live

No signup, no install. Everything below runs on real platform data. The compound browser reads the same records the CLI does. The cultivar matcher uses the same scoring algorithm. The agent reveal streams previously generated output from Dr. Nakamura and Dr. Mullen.

1. Compound browser

Receptor profile, metabolism, FDA status

Loading compound data.
2. Cultivar matcher

Target alkaloid profile, ranked cultivars

Pick at least one directive above to see ranked cultivars.
3. Agent reveal

Invoke a PhD-trained AI expert agent

These are AI composite personas, not real humans. Their names are fictional. Their PhD-grade reasoning comes from grounding in real peer-reviewed literature and federal regulation.

Sample query
Loading.
Click "Stream the response" to watch a pre-recorded CroweLM output.

Each agent's full system prompt lives in the platform source under
crios_nova_psy/agents/psychedelic_specialists.yaml.

Pricing

Three revenue surfaces. Each one buys down a specific class of regulatory or scientific friction.

Tier 1, Subscription

Logic Foundry Psy CLI

$2,500/month

  • Full compound knowledge base access
  • 29 expert agents invocable via CLI
  • Receptor screening and selectivity profiling
  • Cultivar matching with predicted profiles
  • Unlimited queries, one named user

For preclinical discovery teams and academic labs.

Flagship

DEA Schedule I reg-pack

$25,000/application

  • Nine-artifact application drafting packet
  • Cover letter, research protocol, security plan
  • Three operational SOPs (inventory, destruction, emergency)
  • Facility diagram template and DEA Form 225 field map
  • Every artifact CFR-cited inline
  • [LEGAL REVIEW] markers flag every ambiguity

For new Schedule I applicants. Saves roughly $15K and four weeks versus counsel-only drafting.

Tier 1, Engagement

Cultivation consulting

$50,000/engagement

  • Facility-specific cultivation SOP
  • Cultivar selection matched to the clinical endpoint
  • Contamination monitoring protocol
  • Yield and potency benchmarks from a working commercial operation
  • CLI access included for the engagement term

For research facilities scaling for clinical supply.

Tier 2 (Q3 2026): CriOS Nova Psy API, $5,000 per seat per month. Tier 3 (2027): IND-support and DEA-registered compound characterization.

Michael Crowe
Phoenix, AZ Est. 2018 Author, Operator, Architect
Founder

Michael Crowe

Founder and CEO, Crowe Logic, Inc. Chief Mycologist.

Twenty-plus years of applied mycology. Commercial operator, published author, and principal architect of the Crowe Logic AI platform now powering Crowe Psychedelics.

  • Southwest Mushrooms. Founder and operator of a working commercial cultivation business in Phoenix, AZ. Shopify retail, wholesale accounts, Google Ads acquisition, and a documented production pipeline.
  • The Mushroom Grower, Volumes 1 and 2. Published reference work on fungal cultivation, narrated across roughly forty hours of audiobook production and used as the field guide by cultivators worldwide.
  • Crowe Logic AI and CriOS Nova. Principal architect of the production AI platform deployed at ai.southwestmushrooms.com, the chemoinformatics engine licensed by research partners, and the 194-agent system behind this product.
  • Synapse Language and the Crowe Quantum Trinity. PyPI author of synapse-lang and synapse-qubit-flow, scientific-computing languages for quantum chemistry and drug-discovery workflows.
  • Platform portfolio. Ships production products across biotech, controlled-substance regulatory drafting, voice AI (Big O Tires and Crowe Logic voice), grants automation, and multi-agent orchestration.
"I build the operator's tools. The platform in front of you is what happens when twenty years of mycology meet twenty years of systems engineering."

Samples you can read right now

No signup. Real artifacts generated by this platform.

Book a demo

Thirty-minute screen-share of the CLI running on your compound of interest. Leave with a pre-populated reg-pack intake YAML and a decision on fit.

Michael Crowe

Founder and Chief Mycologist
Crowe Logic, Inc.

Who we want to talk to

  • Clinical-stage psychedelic biotechs deploying AI in discovery
  • Research institutions applying for DEA Schedule I registration
  • IRB-approved protocols needing regulatory drafting
  • Commercial mycology operations scaling for clinical supply
  • DEA counsel firms offloading boilerplate drafting to clients
Book a demo